Brunner, Henri and Henning, Frauke and Weber, Matthias (2002) Enantioselective catalysis. Part 143: Astonishingly high enantioselectivity in the transfer hydrogenation of acetophenone with 2-propanol using Ru complexes of the Schiff base derived from (S)-2-amino-2-hydroxy-1,1 '-binaphthyl (NOBIN) and 2-pyridinecarbaldehyde. TETRAHEDRON-ASYMMETRY, 13 (1): PII S0957-. pp. 37-42. ISSN 0957-4166
Full text not available from this repository. (Request a copy)Abstract
A series of bidentate and tridentate (S)-NOBIN derivatives was synthesised and tested as chiral ligands in the Ru-catalysed enantioselective transfer hydrogenation of acetophenone with 2-propanol. Despite the similarities in chemical structure, only the imine derived from (S)-NOBIN and 2-pyridinecarbaldehyde and the corresponding amine (obtained by NaBH4 reduction of the imine) afforded (S)-l-phenylethanol in nearly quantitative yields and outstanding enantioselectivities of up to 97% e.e. (C) 2002 Elsevier Science Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ASYMMETRIC TRANSFER HYDROGENATION; 2-COMPONENT MOLECULAR-CRYSTAL; 2-AMINO-2'-HYDROXY-1,1'-BINAPHTHYL; 2,2'-DIAMINO-1,1'-BINAPHTHYL; 2-NAPHTHYLAMINE; TRANSFORMATION; 2-NAPHTHOL; CHLORIDE; |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Anorganische Chemie > Alumni or Retired Professors > Prof. Dr. Henri Brunner |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 09 Nov 2021 10:05 |
| Last Modified: | 09 Nov 2021 10:05 |
| URI: | https://pred.uni-regensburg.de/id/eprint/40596 |
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