Gleich, Otto and Strutz, Juergen (2002) Age dependent changes in the medial nucleus of the trapezoid body in gerbils. HEARING RESEARCH, 164 (1-2): PII S0378-. pp. 166-178. ISSN 0378-5955
Full text not available from this repository. (Request a copy)Abstract
The results of a quantitative light microscopic analysis of serial glycine immunoreacted sections through the medial nucleus of the trapezoid body (MNTB) of young and old gerbils are presented. Spongiform lesions were prominent in the MNTB of gerbils that were 3 years and older. but were virtually absent in animals below I year of age. In old animals the prevalence and density of spongiform lesions were most pronounced in the caudal MNTB and decreased towards the rostral MNTB. Total MNTB volume and rostro-caudal extent were independent of age and the cross-sectional area of MNTB varied in an identical fashion along the MNTB in young and old gerbils. Mean MNTB soma size (cross-sectional area) varied with the age of the animal. In young gerbils soma size e 2 increased between I and 6 months of age reaching a maximum near 160 mum(2). In old gerbils mean soma size was significantly reduced to 130 mum(2). At all three rostro-caudal positions analyzed along MNTB, soma size varied systematically being largest in the ventrolateral and smallest in the dorso-medial part of MNTB. The reduction of soma size in old animals appeared uniform across MNTB. (C) 2002 Elsevier Science B.V. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SUPERIOR OLIVARY COMPLEX; VENTRAL COCHLEAR NUCLEUS; CENTRAL AUDITORY-SYSTEM; MERIONES-UNGUICULATUS; MONGOLIAN GERBIL; BRAIN-STEM; GLYCINE IMMUNOREACTIVITY; FISCHER-344 RAT; NERVE FIBERS; AGING RATS; brain; auditory cell size; nuclear volume; spongiform lesion |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Hals-Nasen-Ohren-Heilkunde |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 09 Nov 2021 13:32 |
| Last Modified: | 09 Nov 2021 13:32 |
| URI: | https://pred.uni-regensburg.de/id/eprint/40622 |
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