Eruptive multiple lentigo-maligna-like lesions in a patient undergoing chemotherapy with an oral 5-fluorouracil prodrug for metastasizing colorectal carcinoma: A lesson for the pathogenesis of malignant melanoma?

Bogenrieder, Thomas and Weitzel, Christof and Schoelmerich, Juergen and Landthaler, Michael and Stolz, Wilhelm (2002) Eruptive multiple lentigo-maligna-like lesions in a patient undergoing chemotherapy with an oral 5-fluorouracil prodrug for metastasizing colorectal carcinoma: A lesson for the pathogenesis of malignant melanoma? DERMATOLOGY, 205 (2). pp. 174-175. ISSN 1018-8665

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Abstract

Induction of multiple eruptive dermal and atypical melanocytic naevi has frequently been reported in children with malignant haematological diseases and chemotherapy-induced immunosuppression. This is the first report of an adult patient to develop multiple eruptive melanocytic skin lesions while undergoing chemotherapy with an oral 5-fluorouracil prodrug for metastasizing cancer. Our observation adds further evidence to the link between systemic (iatrogenic or intrinsic) immunosuppression and the induction of melanocyte proliferation and transformation. Copyright (C) 2002 S. Karger AG, Basel.

Item Type: Article
Uncontrolled Keywords: MELANOCYTIC NEVI; CANCER; 5-fluorouracil; prodrug; capecitabine; colorectal carcinoma; lentigo maligna
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Dermatologie und Venerologie
Medicine > Lehrstuhl für Innere Medizin I
Depositing User: Dr. Gernot Deinzer
Date Deposited: 15 Nov 2021 15:01
Last Modified: 15 Nov 2021 15:01
URI: https://pred.uni-regensburg.de/id/eprint/40727

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