The past, present and future of HIV-vaccine development: a critical view

Bojak, Alexandra and Deml, Ludwig and Wagner, Ralf (2002) The past, present and future of HIV-vaccine development: a critical view. DRUG DISCOVERY TODAY, 7 (1). pp. 36-46. ISSN 1359-6446

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Abstract

Despite the extensive efforts that have been made to combat AIDS, the global number of HIV-1 infections is still increasing. There is major consent among scientists worldwide, that the development of successful HIV vaccine strategies requires a profound understanding of the epidemiological principles of a viral pandemic, as well as deep insights into the molecular and immunological mechanisms of HIV pathogenesis. This review provides an overview of past and present developments, as well as future aspects of HIV vaccines, and also provides a summary of current clinical trials in man.

Item Type: Article
Uncontrolled Keywords: HUMAN-IMMUNODEFICIENCY-VIRUS; T-LYMPHOCYTE RESPONSES; NEUTRALIZING ANTIBODY-RESPONSES; TYPE-1 INFECTION; IMMUNE-RESPONSES; SERONEGATIVE VOLUNTEERS; RECOMBINANT GP160; CANDIDATE VACCINE; PEPTIDE VACCINE; SUBUNIT VACCINE;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Depositing User: Petra Gürster
Date Deposited: 20 May 2021 06:29
Last Modified: 20 May 2021 06:29
URI: https://pred.uni-regensburg.de/id/eprint/40729

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