Philipp, Alois and Wiesenack, Christoph and Behr, Renate and Schmid, Franz X. and Birnbaum, Dietrich E. (2002) High risk of intraoperative awareness during cardiopulmonary bypass with isoflurane administration via diffusion membrane oxygenators. PERFUSION-UK, 17 (3). pp. 175-178. ISSN 0267-6591
Full text not available from this repository. (Request a copy)Abstract
In cardiac surgery with the aid of extracorporeal circulation (ECC), inhalation anaesthetics can be administered via the oxygenator. Until the recent advent of a new type of diffusion membrane oxygenator, we routinely added the inhalation agent, isoflurane, to the gas flow of a microporous capillary membrane-type oxygenator. Applying this procedure to the diffusion-type oxygenators, the depth of anaesthesia appeared to be affected, which manifested itself through unusually high intraoperative perfusion pressures. This observation led to a prospective randomized study comprising 60 patients and two models of a microporous capillary membrane oxygenator, as well as two models of a diffusion membrane oxygenator. Simultaneous isoflurane concentration measurements at both the gas inlet and outlet ports of the oxygenators showed that, whereas in the microporous capillary-type oxygenators the isoflurane administered was reduced by about 50% during the passage of gas through the device, there was only a minimal transfer of isoflurane in the diffusion-type membrane oxygenators.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SYSTEMIC VASCULAR-RESISTANCE; DESFLURANE; ELIMINATION; SEVOFLURANE; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Anästhesiologie Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 17 Nov 2021 16:26 |
| Last Modified: | 17 Nov 2021 16:26 |
| URI: | https://pred.uni-regensburg.de/id/eprint/40810 |
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