Neumann, I. D. (2002) Involvement of the brain oxytocin system in stress coping: interactions with the hypothalamo-pituitary-adrenal axis. In: Vasopressin and oxytocin: from genes to clinical applications. Progress in Brain Research (139). ELSEVIER SCIENCE BV, AMSTERDAM, pp. 147-162. ISBN 0-444-50982-8
Full text not available from this repository. (Request a copy)Abstract
In response to various ethologically relevant stressors, oxytocin is released not only from neurohypophysial terminals into the blood, but also within distinct brain regions. for example the hypothalamic supraoptic and paraventricular nuclei, the septum and the amygdala in dependence on the quality and intensity of the stressor. Thus, oxytocin secretory activity may accompany the response of the hypothalamo-pituitary-adrenal (HPA) axis to a given stressor. In the present chapter, I try to summarize our efforts to reveal the physiological significance of intracerebrally released oxytocin in rats with respect to the regulation of the HPA axis under basal and stress conditions as well as with respect to behavioural stress responses. The effects of oxytocin appear to depend on the brain region studied and the state of activity of the animal (basal versus stress). In order to reveal interactions between the oxytocin system and the HPA axis, preliminary results a-re presented pointing towards a differential action of glucocorticoids on intracerebral and peripheral oxytocin release.
| Item Type: | Book Section |
|---|---|
| Uncontrolled Keywords: | CORTICOTROPIN-RELEASING FACTOR; MILK-EJECTION REFLEX; PARAVENTRICULAR NUCLEUS; PERIPHERAL RELEASE; LACTATING RATS; MATERNAL-BEHAVIOR; FEMALE RATS; VASOPRESSIN SECRETION; MAGNOCELLULAR NEURONS; ADMINISTERED OXYTOCIN; ACTH; anxiety; maternal behavior; oxytocin receptor antagonist; retrodialysis |
| Subjects: | 500 Science > 590 Zoological sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Zoologie > Tierphysiologie/Neurobiologie (Prof. Dr. Inga Neumann) |
| Depositing User: | Petra Gürster |
| Date Deposited: | 19 May 2021 08:53 |
| Last Modified: | 19 May 2021 08:53 |
| URI: | https://pred.uni-regensburg.de/id/eprint/40848 |
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