Truss-induced macular amyloidosis

Abels, Christoph and Karrer, S. and Landthaler, M. and Szeimies, R. M. (2001) Truss-induced macular amyloidosis. HAUTARZT, 52. pp. 970-973. ISSN 0017-8470

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Abstract

A 80-year-old male presented with a long time history of a localized red-brown macule with superficial lichenification and slight scaling in the right groin. An earlier skin biopsy revealed the presence of amyloid deposits. The patient therefore had a complete internal checkup including a rectal biopsy for exclusion of systemic amyloidosis. However, the laboratory data did not reveal any specific abnormalities including immunoglobulins and Bence-Jones protein. The rectal biopsy was also nonspecific. After skin examination, a rebiopsy was performed at our department showing acanthosis and spongiosis of the epidermis with parakeratosis. A homogenous eosinophilic deposit was present in the upper dermis and stained positive with thio-flavine. At the second visit the patient wore a truss for a right inguinal hernia, perfectly matching the area of the skin lesion. Thus, the diagnosis of a localized macular amyloidosis was confirmed very likely due to permanent local friction. The classification of localized cutaneous amyloidoses should include local trauma as a cause to avoid unnecessary and exhausting internal checkups to exclude systemic involvement.

Item Type: Article
Uncontrolled Keywords: MULTIPLE ENDOCRINE NEOPLASIA; CUTANEOUS AMYLOIDOSES; LICHEN AMYLOIDOSUS; FORMS; amyloid; inguinal hernia; friction
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Dermatologie und Venerologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 06 Dec 2021 10:41
Last Modified: 06 Dec 2021 10:41
URI: https://pred.uni-regensburg.de/id/eprint/41059

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