Framme, Carsten and Roider, J. (2001) Fundus autofluorescence in macular hole surgery. OPHTHALMIC SURGERY AND LASERS, 32 (5). pp. 383-390. ISSN 0022-023X
Full text not available from this repository. (Request a copy)Abstract
BACKGROUND: Macular holes usually are diagnosed by biomicroscopy. Fluorescence angiography (FLA) is helpful especially for judging early stages or pseudoforamina. The importance of fundus-autofluorescence in macular hole surgery was studied. PATIENTS AND METHODS: Twenty-five consecutive patients with macular holes (n = 21) and clinically-similar appearances (n = 4) were examined biomicroscopically. In addition, fundus-autofluorescence and FLA were determined by Heidelberg-Retina-Angiograph (HRA, Heidelberg, Germany). A vitrectomy was performed on 16 patients with macular hole stage II, III, and IV, and membrane peeling was performed if necessary. Platelet-concentrate as an adjuvant agent was used in all surgeries, and all 16 patients were examined afterward. RESULTS: In all patients with macular hole stage III and IV (n = 18), fundus-autofluorescence revealed a marked hyperfluorescent spot in the foveolar region and also a hyperfluorescence in FLA. Patients with macular hole stage II (n = 3) showed a slight punctured hyperautofluorescence and a subtle window-defect in the FLA. Postoperatively, the autofluorescence was normal in all eyes with a closed macular hole (87.5%). In some patients, a variable punctured hyperautofluorescence was noticed (n = 3). In eyes with pseudoforamina, the autofluorescence was normal (n = 4). CONCLUSION: In macular hole diagnostics, fundus-autofluorescence is able to replace invasive fluorescence angiography. The autofluorescence is helpful for the examination of pseudoforamina and might be useful for estimating therapeutic success.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | LASER-SCANNING OPHTHALMOSCOPE; RETINAL-PIGMENT EPITHELIUM; LIPOFUSCIN; FLUORESCENCE; VITRECTOMY; MELANIN; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Augenheilkunde |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 13 Dec 2021 09:19 |
| Last Modified: | 13 Dec 2021 09:19 |
| URI: | https://pred.uni-regensburg.de/id/eprint/41162 |
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