Structurally related immunological effects of triterpenoid saponins

Bernhardt, M. and Sturm, C. and Shaker, K. H. and Paper, D. H. and Franz, Gerhard and Seifert, K. (2001) Structurally related immunological effects of triterpenoid saponins. PHARMAZIE, 56 (9). pp. 741-743. ISSN 0031-7144

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Abstract

The influence of the triterpenoid saponins 1-10 has been investigated on murine spleenocytes in the lymphocyte transformation test and on murine macrophages in an phagocytosis assay. The lymphocyte transformation test and the phagocytosis assay showed that the tested compounds have no stimulating effect. However, a significant inhibition of lymphocyte proliferation by the triterpenoid saponins 2, 6 and 10 was demonstrated.

Item Type: Article
Uncontrolled Keywords: FAGONIA-INDICA;
Subjects: 500 Science > 540 Chemistry & allied sciences
Divisions: Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Franz
Depositing User: Dr. Gernot Deinzer
Date Deposited: 13 Dec 2021 09:49
Last Modified: 13 Dec 2021 09:49
URI: https://pred.uni-regensburg.de/id/eprint/41168

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