Francia, M. Victoria and Haas, Wolfgang and Wirth, Reinhard and Samberger, Elke and Muscholl-Silberhorn, Albrecht and Gilmore, Michael S. and Ike, Yasuyoshi and Weaver, Keith E. and An, Florence Y. and Clewell, Don B. (2001) Completion of the nucleotide sequence of the Enterococcus faecalis conjugative virulence plasmid pAD1 and identification of a second transfer origin. PLASMID, 46 (2). pp. 117-127. ISSN 0147-619X
Full text not available from this repository. (Request a copy)Abstract
pAD1 is a 59.3-kb plasmid in Enterococcus faecalis that has been the subject of intense investigation with regard to its pheromone-inducible conjugation behavior as well as its contribution to virulence. Approximately two-thirds of the pAD1 nucleotide sequence has been previously reported. Here we report on an analysis of the final similar to 22 kb, a significant portion of which is believed to encode structural genes associated with conjugation. The conjugation-regulated region was also found to contain a new (second) origin of conjugative transfer (oriT). A list of open reading frames covering the entire plasmid is presented. (C) 2001 Academic Press.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SEX-PHEROMONE RESPONSE; PAD1-ENCODED STABILITY DETERMINANT; STREPTOCOCCUS-FAECALIS; HEMOLYSIN-BACTERIOCIN; AGGREGATION SUBSTANCE; MOLECULAR CHARACTERIZATION; GENETIC-ANALYSIS; SUBSP ZYMOGENES; PHASE VARIATION; CYTOLYSIN; |
| Subjects: | 500 Science > 570 Life sciences |
| Divisions: | Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Mikrobiologie (Archaeenzentrum) > Prof. Dr. Reinhard Wirth |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 13 Dec 2021 16:23 |
| Last Modified: | 13 Dec 2021 16:23 |
| URI: | https://pred.uni-regensburg.de/id/eprint/41172 |
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