Karrer, Sigrid and Holler, Ernst and Szeimies, Rolf M. (2001) Cutaneous manifestations of graft-versus-host disease. MEDIZINISCHE KLINIK, 96 (8). pp. 457-466. ISSN 0723-5003, 1615-6722
Full text not available from this repository. (Request a copy)Abstract
Graft-versus-host disease (GvHD) is a severe complication of allogeneic stern cell transplantation. GvHD can arise at various time points: acute GvHD occurs during the first 100 days after transplantation in up to 50% of graft recipients. Chronic GvHD develops less frequently in about 30% after the 3rd month following transplantation involving the skin, the liver, the gastrointestinal tract, the eyes, and the neuromuscular apparatus. Early diagnosis of GvHD can be difficult, as drug reactions, viral infections and cutaneous reactions to radiation therapy may have clinical and histological similarities. In this review, the various cutaneous manifestations of GvHD, the histopathologic features, prophylaxis, and therapies of acute and chronic GvHD are discussed according to the recent literature.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | BONE-MARROW TRANSPLANTATION; NECROSIS-FACTOR-ALPHA; HEMATOPOIETIC STEM-CELLS; MATCHED SIBLING DONORS; APLASTIC-ANEMIA; HUMAN RECIPIENTS; ACUTE GVHD; LEUKEMIA; COMPLICATIONS; THERAPY; allogeneic stem cell transplantation; bone marrow transplantation; graft-versus-host disease; acute GvHD; chronic GvHD; sclerodermiform GvHD; lichenoid GvHD; therapy |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie) |
| Depositing User: | Petra Gürster |
| Date Deposited: | 14 May 2021 07:43 |
| Last Modified: | 14 May 2021 07:43 |
| URI: | https://pred.uni-regensburg.de/id/eprint/41192 |
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