Hamer, Okka W. and Gnad, Marcus and Schoelmerich, Juergen and Palitzsch, Klaus-Dieter (2001) Successful treatment of erectile dysfunction and infertility by venesection in a patient with primary haemochromatosis. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 13 (8). pp. 985-988. ISSN 0954-691X
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A 36-year-old patient with primary haemochromatosis presented with erectile dysfunction. Laboratory findings revealed reduced levels of luteinizing hormone (0.4 IU/l; normal range 2-12 IU/l), follicle-stimulating hormone (0.1 IU/l; normal range 1-12 IU/l) and testosterone (0.49 mug/l; normal range 2-8.1 mug/l). We made the diagnosis of secondary hypogonadism due to haemochromatosis, which is generally supposed to be irreversible. Due to consequent venesection therapy, levels of ferritin and transferrin saturation could be normalized, and levels of luteinizing hormone and follicle-stimulating hormone increased to normal ranges. Also, testosterone levels became normal and remained so without any androgen substitution. The patient subsequently regained erectile function and potency. This case underlines the fact that a hypogonadotrophic hypogonadism caused by iron overload can be reversed by a consequent venesection therapy. Eur J Gastroenterol Hepatol 13:985-988 (C) 2001 Lippincott Williams & Wilkins.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HEREDITARY HEMOCHROMATOSIS; GENETIC HEMOCHROMATOSIS; IRON DEPLETION; HYPOGONADOTROPIC HYPOGONADISM; DIAGNOSIS; RECOVERY; haemochromatosis; reversibility; secondary hypogonadism; venesection |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin I |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2021 09:35 |
| Last Modified: | 14 Dec 2021 09:35 |
| URI: | https://pred.uni-regensburg.de/id/eprint/41219 |
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