Spiessl, Hermann and Marienhagen, Jörg and Stoehr, Hannes and Klein, Helmfried E. (2001) Aphasia and dementia. PSYCHIATRISCHE PRAXIS, 28 (5). pp. 246-248. ISSN 0303-4259
Full text not available from this repository.Abstract
Primary progressive aphasia (PPA) is an uncommon neurodegenerative syndrom characterized by a relatively isolated dissolution of language function at the beginning, followed by deterioration of general cognitive function and of activities of daily living after 2 or more years. On account of neuropathological and clinical findings, PPA is supposed to form part of the spectrum of frontotemporal lobar degeneration. We present a case study of a 66-year-old woman with a probable fluent progressive aphasia. She initially experienced word amnesia and developed after 2-3 years gradual regression of word comprehension, over-fluent speech with semantic paraphasias, and at last generalized dementia. In addition to minor bilateral cortical volume reduction on CCT, MRI showed left temporal lobe atrophy involving hippocampus, SPECT revealed reduced uptake left frontal and temporal.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PRIMARY PROGRESSIVE APHASIA; CORTICAL DEGENERATION; SEMANTIC DEMENTIA; TOMOGRAPHY; DISEASE; SPECT; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Abteilung für Nuklearmedizin |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 17 Jan 2022 07:06 |
| Last Modified: | 17 Jan 2022 07:06 |
| URI: | https://pred.uni-regensburg.de/id/eprint/41321 |
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