Dalal, M. A. and Schuld, A. and Haack, M. and Uhr, M. and Geisler, P. and Eisensehr, I. and Noachtar, S. and Pollmaecher, Thomas (2001) Normal plasma levels of orexin A (hypocretin-1) in narcoleptic patients. NEUROLOGY, 56 (12). pp. 1749-1751. ISSN 0028-3878
Full text not available from this repository. (Request a copy)Abstract
Deficient orexin signaling has been shown to cause narcolepsy-like conditions in animals. In human narcolepsy, CSF levels of orexin A (hypocretin-1) were reported to be low in most cases. The authors measured CSF and plasma orexin A levels in patients with narcolepsy and in controls. Confirming earlier studies, they found CSF orexin A levels to be extremely low in patients with narcolepsy. However, plasma orexin A levels did not differ from those observed in controls. These results suggest that orexin deficiency in patients with narcolepsy is a phenomena restricted to the CNS.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Psychiatrie und Psychotherapie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 17 Jan 2022 08:21 |
| Last Modified: | 17 Jan 2022 08:21 |
| URI: | https://pred.uni-regensburg.de/id/eprint/41330 |
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