Treatment of recalcitrant common warts with a ciclopirox-containing lacquer

Szeimies, Rolf-Markus and Wimmershoff, M. B. and Reisberger, E. M. and Landthaler, M. (2001) Treatment of recalcitrant common warts with a ciclopirox-containing lacquer. HAUTARZT, 52 (6). pp. 489-491. ISSN 0017-8470, 1432-1173

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Abstract

Background and Objectives. Anti-inflammatory actions of ciclopirox,an antifungal agent, have been described previously. We assessed the effectiveness of ciclopirox in the treatment of viral warts. Patients/Methods. Twenty-three immunocompetent patients (age 9-61 years) with com mon warts at the hands, feet and in the face resistant to conventional therapy were treated. Following keratolysis with a salicylic acid-containing patch, an 8% ciclopirox lacquer was applied 1-2 times daily. At the beginning and the end of the treatment lesions were photographed and the time span (minimum 4 weeks) until complete resolution was documented. Results. In 7 patients complete remission, and in 12 patients partial remission was achieved. Only 4 patients did not show any effect under topical ciclopirox treatment (mean duration of therapy 3.2 +/-2.1 months). The overall response rate was 82.6%. Local side effects like erythema or pruritus were not reported. Conclusion. Our data suggest that a ciclopirox lacquer may be helpful in the treatment of com mon warts. However, the data have to be confirmed in a randomized controlled trial in the future.

Item Type: Article
Uncontrolled Keywords: PULSED-DYE-LASER; VIRAL WARTS; THERAPY; TRIAL; IMMUNOTHERAPY; CIMETIDINE; PLACEBO; ACID; ciclopirox; verruca vulgaris; topical treatment
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Dermatologie und Venerologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 24 Jan 2022 08:04
Last Modified: 24 Jan 2022 08:04
URI: https://pred.uni-regensburg.de/id/eprint/41375

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