Kaiser, Tanja and Schunkert, Heribert (2001) Cardiovascular adaptations with obesity. HERZ, 26 (3). pp. 194-201. ISSN 0340-9937, 1615-6692
Full text not available from this repository. (Request a copy)Abstract
Background: Obesity is associated with a number of adaptations in the cardiovascular system like arterial hypertension, a hypervolemic circulation or left ventricular hypertrophy. Pathobiochemical Mechanisms: The specific mechanisms underlying these sequelae of obesity are not fully understood. Metabolic factors like insulin-resistance or the elevated activation of the sympathetic a nd the renin-angiotensin-aldosteron system have effects on a number of vascular and cardiac parameters. In addition, elevated serum levels of proinflammatoric parameters like C-reactive protein, interleukin-6 and TNF-alpha are found in patients with obesity. The consequence is a drastic increase of cardiovascular mortality. Conclusion: Depending on the fat distribution and the relation between the increase of body fat mass and fat-free mass different effects on heart and vessels are reported. The most important obesity-associated im plications on the cardiovascular system are discussed below.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | LEFT-VENTRICULAR MASS; BODY-COMPOSITION; BLOOD-PRESSURE; SUDDEN-DEATH; HYPERTROPHY; WOMEN; HYPERTENSION; MORTALITY; DISEASE; INSULIN; obesity; left ventricular hypertrophy; fat-free mass; fat mass |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin II |
| Depositing User: | Petra Gürster |
| Date Deposited: | 14 May 2021 06:27 |
| Last Modified: | 14 May 2021 06:27 |
| URI: | https://pred.uni-regensburg.de/id/eprint/41456 |
Actions (login required)
 |
View Item |
