Permeability characteristics of bovine and human dentin under different pretreatment conditions

Schmalz, Gottfried and Hiller, Karl-Anton and Nunez, Loys J. and Stoll, Juergen and Weis, Kurt (2001) Permeability characteristics of bovine and human dentin under different pretreatment conditions. JOURNAL OF ENDODONTICS, 27 (1). pp. 23-30. ISSN 0099-2399

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Abstract

In order to use bovine dentin instead of human dentin for in vitro adhesion and cytotoxicity tests the permeability characteristics of human and bovine dentin should be similar. In the present study hydraulic conductance (L-p) and diffusional water flux (J(s)) of human and bovine dentin slices were compared. The permeability experiments were performed in a split chamber using tritiated water in physiological saline. L-p and J(s) of bovine dentin were 0.7- to 2.4-fold and 1.1- to 3.5-fold that of human dentin (not statistically significant). For human and bovine dentin L-p and J(s) increased with etching and showed an inverse linear relationship (r(2) greater than or equal to 0.7) with dentin thickness. The variability of bovine data was low (perfusion = 30%, diffusion = 22%) and about half that of the human data. In conclusion bovine dentin near the cementoenamel junction seems to be a suitable alternative for coronal human dentin for in vitro tests with respect to transdentinal permeability characteristics.

Item Type: Article
Uncontrolled Keywords: IN-VITRO; INVITRO;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Zahnerhaltung und Parodontologie > Dr. rer. nat. Karl-Anton Hiller
Depositing User: Dr. Gernot Deinzer
Date Deposited: 01 Mar 2022 09:39
Last Modified: 01 Mar 2022 09:39
URI: https://pred.uni-regensburg.de/id/eprint/41891

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