Schlemm's canal implant. A new method for lowering intraocular pressure in patients with primary open-angle glaucoma?

Spiegel, Detlev and Kobuch, K. and Hill, R. A. and Gross, R. L. (2001) Schlemm's canal implant. A new method for lowering intraocular pressure in patients with primary open-angle glaucoma? OPHTHALMOLOGE, 98 (1). pp. 94-96. ISSN 0941-293X

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Abstract

Background. A surgical technique was developed using a Schlemm's canal implant to bypass the obstruction of outflow of the juxtacanalicular trabecular meshwork in patients with primary open-angle glaucoma. The implant device should also bridge healing processes after trabeculotomy and laser techniques. Patients and methods. An 8- to 15-mm-long silicone tube was implanted in each of two human autopsy eyes connecting the anterior chamber directly with Schlemm's canal. Serial sectioning was performed at two sections of 1-mm length. Results. Implantation of the tube was technically uneventful. Histological examination showed no evidence of mechanical disruption of the endothelial lining of the inner wall of Schlemm's canal. Conclusion. These preliminary results demonstrate the possibility of shunting aqueous directly into Schlemm's canal using a silicone tube. A clinical study in a selected group of patients is planned.

Item Type: Article
Uncontrolled Keywords: EPISCLERAL VENOUS-PRESSURE; LASER TRABECULAR ABLATION; MESHWORK; LTA; Schlemm's canal; glaucoma; implant; silicone
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Augenheilkunde
Depositing User: Dr. Gernot Deinzer
Date Deposited: 07 Mar 2022 10:39
Last Modified: 07 Mar 2022 10:39
URI: https://pred.uni-regensburg.de/id/eprint/41927

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