Sonographic parenchymal and brain perfusion imaging: Preliminary results in four patients following decompressive surgery for malignant middle cerebral artery infarct

Schlachetzki, Felix and Hoelscher, Thilo and Dorenbeck, Ulrich and Greiffenberg, Birgit and Marienhagen, Joerg and Ullrich, Odo-Winfried and Bogdahn, Ulrich (2001) Sonographic parenchymal and brain perfusion imaging: Preliminary results in four patients following decompressive surgery for malignant middle cerebral artery infarct. ULTRASOUND IN MEDICINE AND BIOLOGY, 27 (1). pp. 21-31. ISSN 0301-5629

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Abstract

To investigate new methods of diagnostic transcranial sonography for brain parenchymal, vascular and perfusion imaging, we performed 3-D native tissue harmonic transcranial sonography (3D-nthTCS), 3-D transcranial color-coded duplex sonography (3D-TCCS), and "loss-of-correlation" imaging (LOC-TCCS) in four patients following early hemicraniectomy due to space-occupying "malignant" middle cerebral artery infarction (MMCAI). Three-dimensional datasets, utilizing 3D-nthTCS and 3D-TCCS, were created and up to 10 axial 2-D B-mode image planes, similar to CCT, reconstructed in each patient. Three-dimensional reconstructions of the circle of Willis documented one, persistent carotid-T occlusion and three recanalizations of the MCA. LOC-TCCS, based on stimulated acoustic emission from an ultrasound (US) contrast agent, demonstrated a perfusion deficit in 2 of 3 patients, with regard to their infarcts. Concluding, 3D-nthTCS, 3D-TCCS and LOC-TCCS are promising tools for bedside monitoring, early prognosis and treatment evaluation for MMCAI in the postoperative period. Further studies should be performed to standardize these new methods and evaluate their applications through the intact calvarina. (E-mail: felix.schlachetzki@klinik.uniregensburg.de) (C) 2001 World Federation for Ultrasound in Medicine & Biology.

Item Type: Article
Uncontrolled Keywords: REAL-TIME SONOGRAPHY; ULTRASOUND CONTRAST AGENTS; DUPLEX SONOGRAPHY; BLOOD-FLOW; ULTRASONOGRAPHY; VISUALIZATION; EXPERIENCE; ADULTS; ultrasonography; three-dimensional; transcranial color-coded duplex sonography; ultrasound contrast agents; Levovist (R); native tissue harmonic imaging; stimulated acoustic emission; loss-of-correlation imaging; stroke; middle cerebral artery occlusion
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Neurochirurgie
Medicine > Lehrstuhl für Neurologie
Medicine > Lehrstuhl für Röntgendiagnostik
Medicine > Abteilung für Nuklearmedizin
Depositing User: Dr. Gernot Deinzer
Date Deposited: 08 Mar 2022 07:28
Last Modified: 08 Mar 2022 07:28
URI: https://pred.uni-regensburg.de/id/eprint/41956

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