Keyl, Cornelius and Schneider, Annette and Greene, Richard E. and Passino, Claudio and Spadacini, Giammario and Bandinelli, Gabriele and Bonfichi, Maurizio and Arcaini, Luca and Malcovati, Luca and Bernardi, Luciano (2000) Effects of breathing control on cardiocirculatory modulation in Caucasian lowlanders and Himalayan Sherpas. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, 83 (6). pp. 481-486. ISSN 1439-6319
Full text not available from this repository. (Request a copy)Abstract
This study was performed to investigate the influence of breathing control on the autonomic cardiac regulation at high altitude in adapted and non-adapted awake subjects. We recorded electrocardiogram and pulse oximetry in 14 short-term acclimatized lowlanders and 14 Himalayan Sherpas during resting conditions at an altitude of 5,050 m. Spectrum analysis was performed on synchronized 15 min periods of R-R intervals and the oxygen saturation of arterial blood (SaO2). Despite mean SaO2 being similar in lowlanders and Himalayan Sherpas [78.5 (SD 7.0)% compared to 79.4 (SD5.8)%, respectively], fluctuations in SaO2 were significantly increased in lowlanders compared to Sherpas, thus indicating an unstable regulation of respiration control in lowlanders. Regression analysis demonstrated a significant relationship between spectrum power of SaO2 and the relative power of R-R intervals in the frequency band between 0.01 and 0.08 Hz in lowlanders, but not in Sherpas. Our results demonstrate differences in respiratory and autonomic cardiac control between non-adapted lowlanders and Himalayan high-altitude residents and indicate that unstable breathing control during chronic hypobaric hypoxia is significantly correlated with the autonomic cardiocirculatory regulation.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | HEART-RATE-VARIABILITY; HIGH-ALTITUDE; SLEEP-APNEA; SPECTRAL-ANALYSIS; FAILURE; HUMANS; PATTERNS; CHEMOSENSITIVITY; RESPONSES; RESIDENTS; high altitude; periodic breathing; autonomic nervous system; heart rate variability; respiratory control |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Anästhesiologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 21 Mar 2022 08:01 |
| Last Modified: | 21 Mar 2022 08:01 |
| URI: | https://pred.uni-regensburg.de/id/eprint/41994 |
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