Boehmer, Merle M. and Brandl, Magdalena and Brandstetter, Susanne and Finger, Tamara and Fischer, Wiebke and Pfeifer, Michael and Apfelbacher, Christian (2017) Factors associated with generic health-related quality of life in adult asthma patients in Germany: Cross-sectional study. JOURNAL OF ASTHMA, 54 (3). pp. 325-334. ISSN 0277-0903, 1532-4303
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Objectives: Given a 9% lifetime prevalence of asthma in Germany and the impairment of health-related quality of life (HRQOL) that goes along with it, it is important to understand parameters affecting HRQOL in asthma patients. Objective of this study was therefore to determine factors associated with generic HRQOL in asthma patients. Methods: Data for cross-sectional analyses were obtained from the baseline of an ongoing cohort study. Inclusion criteria: physician-diagnosed asthma; age 18years; disease duration 3months; no acute psychiatric/neurological disease; sufficient knowledge of German. HRQOL was assessed by the Short Form 12 Health Survey Questionnaire (SF-12), which comprises a physical (PCS-12) and a mental component (MCS-12). Information on a broad range of parameters potentially influencing HRQOL was collected by examining the patients' medical records and via a self-administered questionnaire. Those parameters were of socio-demographic, disease-specific, treatment-related or psychosocial nature. We conducted multivariable linear regression analyses to assess determinants of HRQOL. Results: In total, 196 asthma patients participated in the study (mean age: 48years (range: 18-90); 60.2% females). In multivariable analysis, PCS-12 was negatively associated with older age, being female, insufficient disease control, higher number of medications in tablet form and reporting symptoms of depression. MCS-12 was negatively associated with being female, living alone, insufficient disease control, and reporting symptoms of anxiety or depression. Conclusions: Focusing on disease control and screening for depression and anxiety may be promising approaches to improve HRQOL in adult asthma patients. If a patient shows alarming symptoms of anxiety and/or depression, the patient should then be referred for psychiatric treatment.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | SELF-REPORTED ASTHMA; GENDER-DIFFERENCES; PULMONARY-FUNCTION; CONTROL QUESTIONNAIRE; DEPRESSIVE SYMPTOMS; HOSPITAL ANXIETY; IMPACT; VALIDATION; DETERMINANTS; POPULATION; Asthma; health-related quality of life; determinants; SF-12; anxiety; depression |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Institut für Epidemiologie und Präventivmedizin > Medical Sociology |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2018 12:57 |
| Last Modified: | 20 Feb 2019 09:27 |
| URI: | https://pred.uni-regensburg.de/id/eprint/42 |
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