Disciforme keratitis after Bartonella henselae associated Cat Scratch Disease: Identification of a rare ocular complication by PCR

Gabler, Bernhard and Linde, Hans-Joerg and Reischl, Udo and Lohmann, Chris P. (2000) Disciforme keratitis after Bartonella henselae associated Cat Scratch Disease: Identification of a rare ocular complication by PCR. KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE, 217 (5). pp. 299-302. ISSN 0023-2165, 1439-3999

Full text not available from this repository. (Request a copy)

Abstract

Background: Cat scratch disease (CSD) is a common infectious disease, however its association with a disciforme keratitis is to our knowledge a previously unreported ocular complication Patient: A 65-year old female was treated unsuccessfully with topical antibiotics, acyclovir and corticosteroids for several weeks because of a disciforme keratitis. Repeatably, microbiological investigations (microscopy and culture) were negative. 16S rDNA-PCR with subsequent DNA-sequencing on material obtained by corneal scrape identified Bartonella henselae. Based on this result we have initiated a treatment with topical cephotaxim and within a short period of time the cornea healed with a paracentral scar. Conclusion: 165 rDNA-PCR was very helpful in identifying the intracellular sited bacterium Bartonella henselae as the causative pathogen of an unusual form of disciforme keratitis.

Item Type: Article
Uncontrolled Keywords: CHAIN-REACTION PCR; RAPID DIAGNOSIS; ROCHALIMAEA-HENSELAE; MANAGEMENT; INFECTIONS; keratitis; Bartonello henselae; cat scratch disease; PCR
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Augenheilkunde
Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Depositing User: Dr. Gernot Deinzer
Date Deposited: 21 Mar 2022 07:53
Last Modified: 21 Mar 2022 07:53
URI: https://pred.uni-regensburg.de/id/eprint/42108

Actions (login required)

View Item View Item