Synthesis of pyrrolo[3 ',3 ': 2,3]azepino[4,5,6-cd]indol-8,10-diones

Mahboobi, Siavosh and Eluwa, Stella and Koller, Markus and Popp, Alfred and Schollmeyer, Dieter (2000) Synthesis of pyrrolo[3 ',3 ': 2,3]azepino[4,5,6-cd]indol-8,10-diones. JOURNAL OF HETEROCYCLIC CHEMISTRY, 37 (5). pp. 1177-1185. ISSN 0022-152X

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Abstract

3-Amino-4-(3-indolyl)pyrrolin-2,5-diones are condensed with various aldehydes and ketones to the corresponding imines. Under Pietet-Spengler conditions, the latter do not cyclize to pyrrolo-beta -carbolines, but readily yield pyrrolo[3',4':2,3]azepino[4,5,6-cd]indole-8,10-diones.

Item Type: Article
Uncontrolled Keywords: BETA-CARBOLINES; DERIVATIVES; ACID;
Subjects: 500 Science > 540 Chemistry & allied sciences
600 Technology > 615 Pharmacy
Divisions: Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry I (Prof. Elz)
Chemistry and Pharmacy > Institut für Organische Chemie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 28 Mar 2022 08:07
Last Modified: 28 Mar 2022 08:07
URI: https://pred.uni-regensburg.de/id/eprint/42240

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