Secondary resistance among 554 isolates of Helicobacter pylori after failure of therapy

Heep, Markus and Kist, M. and Strobel, S. and Beck, D. and Lehn, Norbert (2000) Secondary resistance among 554 isolates of Helicobacter pylori after failure of therapy. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 19 (7). pp. 538-541. ISSN 0934-9723, 1435-4373

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Abstract

In a study to determine secondary resistance among Helicobacter pylori isolates, gastroenterologists from several German cities submitted over a 3-year period to centre A (Regensburg) or centre B (Freiburg) gastric biopsies from patients in whom one or more therapies to eradicate Helicobacter pylori had failed. Rates of resistance among the collections of 302 (centre A) and 252 (centre B) isolates were, respectively, as follows: to metronidazole, 75% and 66%; to clarithromycin, 58% and 49%; to amoxicillin, 0%; to ciprofloxacin, 9%; to doxycycline, 0%; and to rifampin, 0%. Resistance to clarithromycin was associated with metronidazole resistance in 89% and 85% of the isolates in centre A and centre B, respectively.

Item Type: Article
Uncontrolled Keywords: ERADICATION; INFECTION;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Depositing User: Dr. Gernot Deinzer
Date Deposited: 05 Apr 2022 06:13
Last Modified: 05 Apr 2022 06:13
URI: https://pred.uni-regensburg.de/id/eprint/42341

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