Voelk, Markus and Strotzer, Michael and Lenhart, Markus and Manke, Christoph and Nitz, Wolfgang R. and Seitz, Johannes and Feuerbach, Stefan and Link, Johann (2000) Time-resolved contrast-enhanced MR angiography of renal artery stenosis: Diagnostic accuracy and interobserver variability. AMERICAN JOURNAL OF ROENTGENOLOGY, 174 (6). pp. 1583-1588. ISSN 0361-803X
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OBJECTIVE. The purpose of this study was to evaluate diagnostic accuracy and interobserver variability of time-resolved three-dimensional gadolinium-enhanced MR angiography in the detection of renal artery stenosis in comparison with intraarterial digital subtraction angiography as the standard of reference. SUBJECTS AND METHODS. Forty consecutive patients (age range, 25-81 years; mean. 62.9 +/- 11.9 years) with suspected renal artery stenosis underwent intraarterial digital subtraction angiography and gadolinium-enhanced MR angiography, performed on a 1.5-T system with fast low-angle shot three-dimensional imaging (3.8/1.49 [TRITE], 25 degrees flip angle, 10-sec acquisition time, and 1.5-mm partition thickness). Three time-resolved phases were obtained in a single breath-hold. Digital subtraction angiography and gadolinium-enhanced MR angiography were evaluated by four observers who studied 80 main renal arteries and 19 accessory vessels to evaluate the degree of stenosis. A stenosis reducing the intraarterial diameter by more than 50% was regarded as hemodynamically significant. Interobserver variability was calculated. RESULTS. Only one gadolinium-enhanced MR angiography study was not of diagnostic quality, as a result of failure of the power injector. All main branches were of diagnostic quality in 38 (97.4%) of the remaining 39 gadolinium-enhanced MR angiography studies. Seventeen (89.5%) of 19 accessory renal arteries were depicted with gadolinium-enhanced MR angiography. The overall sensitivity for significant stenoses was 92.9%. The overall specificity was 83.4%, and the overall accuracy was 85.9%. Interobserver variability of gadolinium-enhanced MR angiography exceeded that of digital subtraction angiography. CONCLUSION. Time-resolved three-dimensional gadolinium-enhanced MR angiography is a useful noninvasive method of screening suspected renal artery stenosis because of its easy application, short examination time, and high sensitivity despite of its higher interobserver variability.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | MAGNETIC-RESONANCE ANGIOGRAPHY; ABDOMINAL AORTIC-ANEURYSMS; SINGLE-BREATH HOLD; ANGIOPLASTY; FAILURE; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Röntgendiagnostik |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 26 Apr 2022 09:18 |
| Last Modified: | 26 Apr 2022 09:18 |
| URI: | https://pred.uni-regensburg.de/id/eprint/42410 |
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