Muders, Frank and Elsner, Dietmar (2000) Animal models of chronic heart failure. PHARMACOLOGICAL RESEARCH, 41 (6). pp. 605-612. ISSN 1043-6618
Full text not available from this repository.Abstract
Chronic heart failure is associated with multiple pathophysiological alterations and adaptations, such as marked anatomic and biochemical changes of the myocardium, left ventricular dysfunction and dilatation, increased systemic vascular resistance, and activation of neurohumoral and cytokine systems. The use of animal models has provided a new insight into the complex pathogenesis of this syndrome and supplemented clinical experience. However, all of the animal models used have advantages and limitations, and the transfer from experimental to human heart failure needs critical evaluation. The current review will focus upon new aspects of rat and rabbit models of heart failure. (C) 2000 Academic Press.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PRESSURE-OVERLOAD HYPERTROPHY; LEFT-VENTRICULAR HYPERTROPHY; SPONTANEOUSLY HYPERTENSIVE RAT; ATRIAL NATRIURETIC PEPTIDE; RENIN-ANGIOTENSIN SYSTEM; CARDIAC MYOCYTE SIZE; MYOCARDIAL-INFARCTION; GENE-EXPRESSION; ADRIAMYCIN CARDIOMYOPATHY; DIABETIC CARDIOMYOPATHY; heart failure; rat; rabbit |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin II |
| Depositing User: | Petra Gürster |
| Date Deposited: | 28 Apr 2021 10:43 |
| Last Modified: | 28 Apr 2021 10:43 |
| URI: | https://pred.uni-regensburg.de/id/eprint/42463 |
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