Steinmeyer, J. and Bolder, Ulrich (2000) Intestinal functions in the critically ill patients. CHIRURGISCHE GASTROENTEROLOGIE, 16. pp. 13-22. ISSN 0177-9990
Full text not available from this repository. (Request a copy)Abstract
The gastrointestinal tract is an organ of digestion and absorption which is metabolically active and has specific nutrient requirements. Both in health and critical illness, it has an additional function as a major barrier, protecting the body from harmful intraluminal pathogens and antigenic molecules. However, there is a great body of evidence that trauma, sepsis or other critical illnesses lead to derangements in the barrier function of the gut, which results in a blood-stream invasion by gut-derived pathogens, leading to 'primary' bacteraemias or fungaemias. Under experimental and certain clinical conditions, stimulating the gut attenuates these stress response and prevents the gut-associated lymphoid tissue, the body's major defender of moist mucosal surfaces. A better understanding of gut function and improved nutrient delivery has clinical implications on the treatment of critically ill patients.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TOTAL PARENTERAL-NUTRITION; ISCHEMIA-REPERFUSION INJURY; HUMAN PEYERS PATCHES; BACTERIAL TRANSLOCATION; NITRIC-OXIDE; HEMORRHAGIC-SHOCK; ORGAN FAILURE; GROWTH-FACTOR; BURN INJURY; AMINO-ACID; intestinal barrier function; bacterial translocation; critically ill patients; MODS; SIRS |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Chirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 24 May 2022 13:18 |
| Last Modified: | 24 May 2022 13:18 |
| URI: | https://pred.uni-regensburg.de/id/eprint/42774 |
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