Moser, M and Stempfl, T and Li, Y and Glynn, P and Buttner, R and Kretzschmar, D (2000) Cloning and expression of the murine sws/NTE gene. MECHANISMS OF DEVELOPMENT, 90 (2). pp. 279-282. ISSN 0925-4773,
Full text not available from this repository.Abstract
The Drosophila neurodegeneration gene swiss-cheese encodes a neuronal protein apparently involved in glia-neuron interaction and is homologous to human NTE, the molecular target of organophosphate-induced neuropathy. The isolated Msws/NTE gene is 96% identical to NTE. During development the Msws transcript is expressed in the embryonic respiratory system, different epithelial structures and strongly in the spinal ganglia. Postnatally, Msws mRNA is expressed in all brain areas, with an increasingly restrictive pattern, In adult mice expression is most prominent in Purkinje cells. granule cells and pyramidal neurons of the hippocampus and some large neurons in the medulla oblongata, nucleus dentatus and pens. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | NEUROPATHY TARGET ESTERASE; DROSOPHILA; Drosophila swiss-cheese; mouse swiss-cheese; neuropathy target esterase; neurodegeneration; gene expression; nervous system |
| Subjects: | 500 Science > 570 Life sciences 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Pathologie Biology, Preclinical Medicine > Institut für Zoologie > Entwicklungsbiologie (Prof. Dr. Stephan Schneuwly) |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 21 May 2021 07:52 |
| Last Modified: | 21 May 2021 07:52 |
| URI: | https://pred.uni-regensburg.de/id/eprint/42864 |
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