Pinto, F. and Grosse-Buening, S. and Karsai, S. and Weiss, C. and Baeumler, W. and Hammes, S. and Felcht, M. and Raulin, C. (2017) Neodymium-doped yttrium aluminium garnet (Nd:YAG) 1064-nm picosecond laser vs. Nd:YAG 1064-nm nanosecond laser in tattoo removal: a randomized controlled single-blind clinical trial. BRITISH JOURNAL OF DERMATOLOGY, 176 (2). pp. 457-464. ISSN 0007-0963, 1365-2133
Full text not available from this repository. (Request a copy)Abstract
Background For decades, nanosecond lasers (NSLs) have been used to remove tattoos. Since 2012, pulses of picosecond lasers (PSLs) have been available for tattoo removal. Based on a few observational studies, the claim has been made that PSLs are considerably more effective while showing fewer side-effects in comparison with NSLs. Objectives To compare the efficacy and side-effects of a PSL side by side with an NSL for tattoo removal. Methods Twenty-one patients with 30 black tattoos were treated with PSL and NSL in a split-study design in two sessions at intervals of 6 weeks. The safety and efficacy of laser treatments were determined by blinded observers assessing randomized digital photographs in this prospective clinical study. The primary end point was the clearance of the tattoos ranging in quartiles from 0% to 100%; secondary end points were side-effects and pain. Results The average clearance overall as evaluated showed no statistical difference between NSL and PSL (P = 1.00). Using a visual analogue scale (0 = no pain, 10 = maximum pain), a value of 3.8 +/- 1.0 was reported for the PSL, which was statistically different from NSL (7.9 +/- 1.1, P < 0.001). Transient side-effects were observed, as well as hypo-and hyperpigmentation, but there was no statistically significant difference between PSL and NSL. Conclusions After two treatments of black tattoos with a neodymium-doped yttrium aluminium garnet laser (1064 nm), the use of picosecond pulses does not provide better clearance than nanosecond pulses. However, pain is less severe when using a PSL.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | 2-PHOTON ABSORPTION; CLEARANCE; ASSOCIATION; SPONSORSHIP; MOTIVATION; INDUSTRY; PIGMENT; DESIGN; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 14 Dec 2018 13:01 |
| Last Modified: | 12 Feb 2019 12:43 |
| URI: | https://pred.uni-regensburg.de/id/eprint/431 |
Actions (login required)
 |
View Item |
