Sag, Sabine Julia Maria and Menhart, Karin and Grosse, Jirka and Hitzenbichler, Florian and Hanses, Frank and Mohr, Arno and Salzberger, Bernd and Zerdzitzki, Matthaus and Hilker, Michael and Rupprecht, Leopold and Hellwig, Dirk and Schmid, Christof and Maier, Lars Siegfried and Sag, Can Martin (2020) Diagnostic value of FDG PET/CT imaging in patients with surgically managed infective endocarditis: results of a retrospective analysis at a tertiary center. JOURNAL OF NUCLEAR CARDIOLOGY. ISSN 1071-3581, 1532-6551
Full text not available from this repository. (Request a copy)Abstract
Background We assessed the diagnostic value of FDG PET/CT in a real-world cohort of patients with surgically managed infective endocarditis (IE). Methods We performed a retrospective analysis of all patients hospitalized in a tertiary IE referral medical center from January 2014 to October 2018 fulfilling the following criteria: ICD-10 code for IE and OPS code for both, heart surgery and FDG PET/CT. Results Final analysis included 29 patients, whereof 28 patients had surgically proven IE. FDG PET/CT scan was true-positive in 15 patients (sensitivity (SEN) 56%) and false-negative in 12 patients. Combination of Duke criteria (DC) with FDG PET/CT scan resulted in gain of SEN for all patients with confirmed IE (SEN of DC 79% vs SEN of combination DC and FDG PET/CT 89%), driven by a relevant gain in PVE patients only (SEN of DC 78% vs SEN of combination DC and FDG PET/CT 94%). Interestingly, higher prosthesis age was observed in patients with false-negative scans. Conclusions We found a SEN of 56% for FDG PET/CT in a real-world cohort of patients with surgically proven IE which was associated with a 16% gain of IE diagnosis in patients with PVE when combined with DC.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY; Inflammation; PET; image interpretation |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie Medicine > Lehrstuhl für Innere Medizin II Medicine > Abteilung für Nuklearmedizin |
| Depositing User: | Petra Gürster |
| Date Deposited: | 22 Apr 2021 04:58 |
| Last Modified: | 22 Apr 2021 04:58 |
| URI: | https://pred.uni-regensburg.de/id/eprint/43104 |
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