Markowiak, Till and Hofmann, Hans-Stefan and Ried, Michael (2020) Classification and staging of thymoma. JOURNAL OF THORACIC DISEASE, 12 (12). pp. 7607-7612. ISSN 2072-1439, 2077-6624
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The appropriate therapy and prognosis of patients with thymic malignancies is decisively influenced by the local extent and dissemination of the tumor. For this reason, a staging system that reflects these factors is essential. Mainly the Masaoka-Koga classification, which was introduced in 1994, has been applied for this purpose. The rarity of thymic malignancies makes it difficult not only to establish internationally standardized diagnostics and treatment, but also to progress staging. Besides, efforts were made to adapt the classification into a tumor-node-metastasis-based (TNM) system for standardization with the staging of other tumor entities. The 2017 published 8th edition of the TNM Classification of Malignant Tumors introduced several adjustments based on a proposal of the International Association for the Study of Lung Cancer (IASLC) and the International Thymic Malignancy Interest Group (ITMIG). Compared to the Masaoka-Koga classification, surgically good resectable tumor involvements like pericardium, mediastinal fat or mediastinal pleura have been shifted to lower stages. Thus, even more than in Masaoka-Koga classification, tumors are basically divided into completely resectable and thus surgically treatable tumors (stage I, II, IIIA) and advanced stages (stage IIIB, IVA and IVB) that require multimodal therapy.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | THYMIC EPITHELIAL TUMORS; SURGICAL RESECTION; MASAOKA; SYSTEM; THYMECTOMY; RECURRENCE; PERFUSION; SURVIVAL; Thymoma; thymic carcinoma (TC); tumor staging; hyperthermic intrathoracic chemotherapy |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Abteilung für Thoraxchirurgie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 21 Apr 2021 12:40 |
| Last Modified: | 21 Apr 2021 12:40 |
| URI: | https://pred.uni-regensburg.de/id/eprint/43188 |
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