European Code against Cancer 4th Edition: Alcohol drinking and cancer

Scoccianti, Chiara and Cecchini, Michele and Anderson, Annie S. and Berrino, Franco and Boutron-Ruault, Marie-Christine and Espina, Carolina and Key, Timothy J. and Leitzmann, Michael and Norat, Teresa and Powers, Hilary and Wiseman, Martin and Romieu, Isabelle (2015) European Code against Cancer 4th Edition: Alcohol drinking and cancer. CANCER EPIDEMIOLOGY, 39. S67-S74. ISSN 1877-7821, 1877-783X

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Abstract

Alcohol consumption is the third leading risk factor for disease and mortality in Europe. The International Agency for Research on Cancer (IARC) Monographs provide strengthened evidence that the consumption of alcoholic beverages is causally associated with cancers of the oral cavity, pharynx, larynx, oesophagus, liver, colorectum and female breast, even for low and moderate alcohol intakes. The risk of cancer increases in a dose-dependent manner, and the higher the amount of alcohol consumed, the higher the risk of developing cancer. Several biological mechanisms explain the carcinogenicity of alcohol; among them, ethanol and its genotoxic metabolite acetaldehyde play a major role. Taking all this evidence into account, a recommendation of the 4th edition of the European Code against Cancer (ECAC) is: "If you drink alcohol of any type, limit your intake. Not drinking alcohol is better for cancer prevention." (C) 2015 International Agency for Research on Cancer; Licensee ELSEVIER Ltd

Item Type: Article
Uncontrolled Keywords: POSTMENOPAUSAL BREAST-CANCER; AERODIGESTIVE TRACT CANCER; MTHFR C677T POLYMORPHISM; SQUAMOUS-CELL CARCINOMA; CORONARY-HEART-DISEASE; COLORECTAL-CANCER; POOLED ANALYSIS; NECK-CANCER; UNITED-STATES; METHYLENETETRAHYDROFOLATE REDUCTASE; Alcohol drinking; Cancer; Ethanol; Acetaldehyde; Disease; Primary prevention; Europe
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Institut für Epidemiologie und Präventivmedizin
Depositing User: Dr. Gernot Deinzer
Date Deposited: 30 Apr 2019 14:12
Last Modified: 30 Apr 2019 14:12
URI: https://pred.uni-regensburg.de/id/eprint/4323

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