NORMAL AGE- AND SEX-RELATED VALUES OF THE OPTIC NERVE SHEATH DIAMETER AND ITS DEPENDENCY ON POSITION AND POSITIVE END-EXPIRATORY PRESSURE

Ertl, Michael and Knuppel, Christin and Veitweber, Martina and Wagner, Andrea and Pfister, Karin and Wendl, Christina and Baldaranov, Dobri and Beck, Jurgen and Linker, Ralf A. and Schlachetzki, Felix (2020) NORMAL AGE- AND SEX-RELATED VALUES OF THE OPTIC NERVE SHEATH DIAMETER AND ITS DEPENDENCY ON POSITION AND POSITIVE END-EXPIRATORY PRESSURE. ULTRASOUND IN MEDICINE AND BIOLOGY, 46 (12). pp. 3279-3285. ISSN 0301-5629, 1879-291X

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Abstract

Optic nerve sheath diameter (ONSD) sonography is a reliable method for evaluation of intracranial pressure, yet there is a lack of reliable normal values. In the study described here, we established normal ONSD values in three different age groups and both sexes. One hundred eighty-seven volunteers without central nervous system disease were enrolled in this prospective study. ONSD measurements were taken in volunteers in the supine and upright positions and after application of positive end-expiratory pressure (PEEP). Normal ONSD values were 4.9-5.3 mm (patient age range: 20-85), with significant differences between men and women (p < 0.001). ONSD values increased with age (Delta = 0.34 mm, p < 0.001). There were no differences compared with the upright position but application of PEEP led to significantly increased ONSD values (Delta = 0.21 mm, p = 0.008). ONSD values increased with age, correlated well with the width of the third ventricle, were significantly lower in the female cohort and quickly responded to PEEP, especially in women. (E-mail: Michael.Ertl@uk-augsburg.de) (C) 2020 World Federation for Ultrasound in Medicine & Biology. All rights reserved.

Item Type: Article
Uncontrolled Keywords: SONOGRAPHIC ASSESSMENT; ULTRASOUND; Optic nerve sheath diameter; Transorbital ultrasound; Normal values; Dynamics; Positive end-expiratory pressure
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Abteilung für Gefäßchirurgie
Medicine > Lehrstuhl für Neurochirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 08 Mar 2021 07:42
Last Modified: 08 Mar 2021 07:42
URI: https://pred.uni-regensburg.de/id/eprint/43315

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