Current Challenges in the Post-Transplant Care of Liver Transplant Recipients in Germany

Herzer, Kerstin and Sterneck, Martina and Welker, Martin-Walter and Nadalin, Silvio and Kirchner, Gabriele and Braun, Felix and Malessa, Christina and Herber, Adam and Pratschke, Johann and Weiss, Karl Heinz and Jaeckel, Elmar and Tacke, Frank (2020) Current Challenges in the Post-Transplant Care of Liver Transplant Recipients in Germany. JOURNAL OF CLINICAL MEDICINE, 9 (11): 3570. ISSN , 2077-0383

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Abstract

Improving long-term patient and graft survival after liver transplantation (LT) remains a major challenge. Compared to the early phase after LT, long-term morbidity and mortality of the recipients not only depends on complications immediately related to the graft function, infections, or rejection, but also on medical factors such as de novo malignancies, metabolic disorders (e.g., new-onset diabetes, osteoporosis), psychiatric conditions (e.g., anxiety, depression), renal failure, and cardiovascular diseases. While a comprehensive post-transplant care at the LT center and the connected regional networks may improve outcome, there is currently no generally accepted standard to the post-transplant management of LT recipients in Germany. We therefore described the structure and standards of post-LT care by conducting a survey at 12 German LT centers including transplant hepatologists and surgeons. Aftercare structures and form of cost reimbursement considerably varied between LT centers across Germany. Further discussions and studies are required to define optimal structure and content of post-LT care systems, aiming at improving the long-term outcomes of LT recipients.

Item Type: Article
Uncontrolled Keywords: LONG-TERM MANAGEMENT; DE-NOVO MALIGNANCIES; RISK-FACTORS; DEPRESSIVE SYMPTOMS; NONALCOHOLIC STEATOHEPATITIS; ORGAN-TRANSPLANTATION; MEDIATED REJECTION; FOLLOW-UP; SURVIVAL; DISEASE; liver transplantation; long-term outcome; post-liver transplantation management; liver transplantation center; aftercare structures; Germany
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Chirurgie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 08 Mar 2021 10:17
Last Modified: 08 Mar 2021 10:17
URI: https://pred.uni-regensburg.de/id/eprint/43454

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