Scientific Rationale for the Directive on Opioid Substitution Treatment of the German Medical Association: A Summary

Kunstmann, Wilfried and Specka, Michael and Wodarz, Norbert and Scherbaum, Norbert (2020) Scientific Rationale for the Directive on Opioid Substitution Treatment of the German Medical Association: A Summary. GESUNDHEITSWESEN, 82 (11). pp. 915-919. ISSN 0941-3790, 1439-4421

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Abstract

Background According to the Narcotic Drugs Prescription Ordinance (BtMVV), the German Medical Association was commissioned to issue a directive on opioid substitution treatment (OST) based on the current state of scientific medical knowledge. Method For the publication of the initial version of the German Medical Association's directive in 2002, an extensive literature research had been conducted, categorizing the results by levels of evidence. Subsequent revisions in 2010 and 2017 included recent systematic reviews, studies of evidence levels I-III and international guidelines. Results OST showed its potential in the pursuit of health- and addiction-related as well as psychological and social goals. There was a decline in the rate of mortality, and high risk consumption of illegally acquired opioids was eliminated in 70 to 80% of patients in OST. Psycho-social assistance was found to enhance treatment outcome. Scientific evidence was lacking for the identification of patient groups suitable for different duration of take-home prescription. Conclusions With its 2017 amendment, the guideline of the German Medical Association was revised on the basis of the current state of science on substitution treatment. This creates more legal certainty for doctors, and treatment can be delivered in accordance with the existing scientific knowledge. Whether the effects of OST observed in this study have an impact on the care of opioid addicts by attracting more doctors to participate in their treatment needs further evaluation.

Item Type: Article
Uncontrolled Keywords: METHADONE-MAINTENANCE; MORTALITY; METAANALYSIS; RISK; Opioid substitution treatment; treatment goals; treatment monitoring; take-home prescription; psycho-social assistance; medication
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Psychiatrie und Psychotherapie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 08 Mar 2021 10:14
Last Modified: 08 Mar 2021 10:14
URI: https://pred.uni-regensburg.de/id/eprint/43473

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