Safety and effectiveness of percutaneous sclerotherapy for venous disorders of the labia majora in patients with vascular malformations

Brill, Richard and Deistung, Andreas and Gussew, Alexander and Goldann, Constantin and Stangl, Franz and Uller, Wibke and Rosendahl, Jonas and Wildgruber, Moritz and Wohlgemuth, Walter Alexander (2020) Safety and effectiveness of percutaneous sclerotherapy for venous disorders of the labia majora in patients with vascular malformations. JOURNAL OF VASCULAR SURGERY-VENOUS AND LYMPHATIC DISORDERS, 8 (6). pp. 1083-1089. ISSN 2213-333X,

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Abstract

Objective: The aim of this study was to evaluate the safety and clinical outcomes of percutaneous sclerotherapy of venous disorders of the labia majora in patients with vascular malformations of the lower limbs. Methods: Thirty percutaneous sclerotherapy treatments were performed over a 6-year period among 17 female patients with symptomatic venous malformation (VM) or secondary varicosis of the labia majora. Four patients were treated with sclerotherapy alone, 13 patients had additional procedures to control the VM before sclerotherapy. Polidocanol was used as sclerosant. Indications for sclerotherapy included pain, bleeding, thrombophlebitis, and swelling. Genitourinary symptoms were recorded. The number of treatments and procedure-related complications were registered. Complications were classified according to the Society of Interventional Radiology (SIR) classification system (grade A-E). The 3-month postintervention follow-up included magnetic resonance imaging, clinical examination, and a symptom-related questionnaire. If no reintervention was necessary, consultation was scheduled biannually. Results: All patients had local swelling and pain; only a fraction of the patients had further symptoms with bleeding or thrombophlebitis (47% each). Eight patients required reintervention. No major complications were observed; minor complications such as postprocedural swelling occurred in 29% (SIR grade A), pain occurred in 17% (SIR grade B), and skin blistering developed in 5% (SIR grade B). Upon follow-up examination after a median of 40 months, 76% showed complete relief of symptoms, and 23% reported partial relief. All patients reported a substantial reduction in pain (75% >5 points in visual analogue scale) and swelling (88% complete cessation). Conclusions: Percutaneous sclerotherapy is a safe and effective treatment option of VM and secondary varicosis of the labia majora.

Item Type: Article
Uncontrolled Keywords: VULVAR VARICOSITIES; ANOMALIES; Female; Adult; Child; Vulva; Pain; Angiography; Magnetic resonance imaging; Sclerotherapy; Sclerosing solutions
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Röntgendiagnostik
Depositing User: Dr. Gernot Deinzer
Date Deposited: 08 Mar 2021 11:28
Last Modified: 08 Mar 2021 11:28
URI: https://pred.uni-regensburg.de/id/eprint/43486

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