Litzka, Christian and Leebmann, Hubert and Wiesinger, Hellmuth and Kirchner, Thomas and Seelbach-Goebel, Birgit and Haeusler, Sebastian Franz Martin (2020) Management of intra-abdominal dysgerminoma During pregnancy - A Case Report and Literature Review. ZEITSCHRIFT FUR GEBURTSHILFE UND NEONATOLOGIE, 224 (05). pp. 306-314. ISSN 0948-2393, 1439-1651
Full text not available from this repository. (Request a copy)Abstract
Introduction Dysgerminomas are rare malignant germ cell tumors. They usually arise from the ovary, but case reports describing extraovarian dysgerminomas do exist. When treated adequately the disease has a good prognosis. Dysgerminomas diagnosed during pregnancy are very rare. Methodology Report of extraovarian intra-abdominal dysgerminoma during pregnancy. Systematic literature review. Case report A 35-year-old second gravida was diagnosed with a suspected intra-abdominal mass at 20 gestational weeks. During an exploratory laparotomy, a tumor infiltrating the transverse colon and histologically identified as a dysgerminoma was resected. Ovaries were clinically unremarkable. The induction of chemotherapy was postponed until after delivery. At 34 gestational weeks the patient underwent cesarean section and tumor debulking. Four cycles of bleomycin, etoposide and cisplatin were administered. After 12 months, cystic ovaries were found. Hysterectomy with bilateral adnexectomy was performed but no malignancy found. After 16 months, the patient was still in complete remission. Conclusion We describe the first-ever published dysgerminoma in gravida primarily evolving intraabdominally and not affecting the ovaries. The decision for cytoreductive surgery, prolongation of pregnancy and postponing chemotherapy until after delivery combined the best benefit for the baby with a good maternal prognosis. Due to limited data regarding dysgerminomas in pregnancy, individual interdisciplinary concepts are mandatory.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | GERM-CELL TUMORS; IMPACT; FETAL; Dysgerminoma; extraovarian; pregnancy; malignoma |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Frauenheilkunde und Geburtshilfe (Schwerpunkt Geburtshilfe) |
| Depositing User: | Petra Gürster |
| Date Deposited: | 20 Apr 2021 10:17 |
| Last Modified: | 20 Apr 2021 10:17 |
| URI: | https://pred.uni-regensburg.de/id/eprint/43651 |
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