Dalbavancin as long-term suppressive therapy for patients with Gram-positive bacteremia due to an intravascular source-a series of four cases

Hitzenbichler, Florian and Mohr, Arno and Camboni, Daniele and Simon, Michaela and Salzberger, Bernd and Hanses, Frank (2021) Dalbavancin as long-term suppressive therapy for patients with Gram-positive bacteremia due to an intravascular source-a series of four cases. INFECTION, 49 (1). pp. 181-186. ISSN 0300-8126, 1439-0973

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Abstract

We present four cases with Gram-positive bacteremia (pathogens: MRSAn = 1, Enterococcusspp.n = 3) due to an intravascular source (left ventricular assist device:n = 2, transfemoral aortic valve implantationn = 1, prosthetic aortic valve:n = 1) where no curative treatment was available. These patients received indefinite, chronic suppressive (palliative) therapy with dalbavancin (500 mg weekly or 1000 mg biweekly regimens). Outcomes and clinical characteristics are described; treatment was effective in suppression of bacteremia in all patients over several months (range: 1 to more than 12 months), we observed no relevant side effects.

Item Type: Article
Uncontrolled Keywords: SKIN; Dalbavancin; Bacteremia; Intravascular infection; Suppressive therapy; LVAD; Endocarditis
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie
Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Medicine > Institut für Epidemiologie und Präventivmedizin
Depositing User: Dr. Gernot Deinzer
Date Deposited: 18 May 2021 18:45
Last Modified: 18 May 2021 18:45
URI: https://pred.uni-regensburg.de/id/eprint/43767

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