Faulkner, Lawrence and Verna, Marta and Rovelli, Attilio and Agarwal, Rajat Kumar and Dhanya, Rakesh and Parmar, Lalith and Sedai, Amit and Kumari, Ankita and Ramprakash, Stalin and Raghuram, C. P. and Mehta, Pallavi and Elizabeth, Sandeep and Khalid, Sadaf and Batool, Aliya and Ghilani, Sarah Khan and Fatima, Itrat and Zara, Tatheer and Marwah, Priya and Soni, Rajpreet and Trivedi, Deepa and Conter, Valentino and Canesi, Marta and Othman, Dosti and Faeq, Vian and Kleinschmidt, Katharina and Yesillipek, Akif and Lam, Catherine G. and Howard, Scott C. and Corbacioglu, Selim (2021) Setting up and sustaining blood and marrow transplant services for children in middle-income economies: an experience-driven position paper on behalf of the EBMT PDWP. BONE MARROW TRANSPLANTATION, 56. pp. 536-543. ISSN 0268-3369, 1476-5365
Full text not available from this repository. (Request a copy)Abstract
Severe blood disorders and cancer are the leading cause of death and disability from noncommunicable diseases in the global pediatric population and a major financial burden. The most frequent of these conditions, namely sickle cell disease and severe thalassemia, are highly curable by blood or bone marrow transplantation (BMT) which can restore a normal health-related quality of life and be cost-effective. This position paper summarizes critical issues in extending global access to BMT based on ground experience in the start-up of several BMT units in middle-income countries (MICs) across South-East Asia and the Middle East where close to 700 allogeneic BMTs have been performed over a 10-year period. Basic requirements in terms of support systems, equipment, and consumables are summarized keeping in mind WHO's model essential lists and recommendations. BMT unit setup and maintenance costs are summarized as well as those per transplant. Low-risk BMT is feasible and safe in MICs with outcomes comparable to high-income countries but at a fraction of the cost. This report might be of assistance to health care institutions in MICs interested in developing hematopoietic stem cell transplantation services and strengthening context appropriate tertiary care and higher medical education.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | STEM-CELL TRANSPLANTATION; BONE-MARROW; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Abteilung für Pädiatrische Hämatologie, Onkologie und Stammzelltransplantation |
| Depositing User: | Petra Gürster |
| Date Deposited: | 14 Apr 2021 06:39 |
| Last Modified: | 14 Apr 2021 06:39 |
| URI: | https://pred.uni-regensburg.de/id/eprint/43847 |
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