Philipp-Dormston, Wolfgang G. and Karrer, Sigrid and Petering, Holger and Ulrich, Claas and Dirschka, Thomas and Berking, Carola and Lonsdorf, Anke S. and Gerber, Peter Arne and Radakovic, Sonja and Hunger, Robert E. and Szeimies, Rolf-Markus (2015) Daylight PDT with MAL - current data and practical recommendations of an expert panel. JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 13 (12). pp. 1240-1249. ISSN 1610-0379, 1610-0387
Full text not available from this repository. (Request a copy)Abstract
Photodynamic Therapy (PDT) is one of the standard treatment modalities for actinic keratoses (AKs). Daylight PDT (DL-PDT) with MAL cream is a rather recent development, which, instead of an artificial light source, uses daylight for the activation of the photosensitizer. The present review summarizes available data based on a selective literature search, highlights practical aspects, and reflects the authors' expert knowledge in using DL-PDT. With respect to efficacy, study data shows that DL-PDT is noninferior to conventional PDT (cPDT). However, given that DL-PDT is markedly less painful, it is significantly better tolerated than cPDT. In Europe, DL-PDT can be performed from March to October, on sunny as well as on cloudy days. UV protection of untreated areas of the body should be observed. Outside temperature should not fall below 10 degrees C. On hot days, patients should be advised to stay in the shade if necessary. Representing a useful addition to current therapeutic options, DL-PDT with MAL cream is, among others, suitable for patients with field cancerization and/or those who have experienced severe pain associated with cPDT.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TOPICAL METHYL-AMINOLEVULINATE; MEDIATED PHOTODYNAMIC THERAPY; ORGAN TRANSPLANT RECIPIENTS; RANDOMIZED CONTROLLED-TRIAL; MULTIPLE ACTINIC KERATOSES; EMITTING DIODE LIGHT; FIELD CANCERIZATION; EUROPEAN CONSENSUS; DOUBLE-BLIND; MULTICENTER; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Dermatologie und Venerologie |
| Depositing User: | Petra Gürster |
| Date Deposited: | 26 Aug 2020 10:03 |
| Last Modified: | 26 Aug 2020 10:03 |
| URI: | https://pred.uni-regensburg.de/id/eprint/4403 |
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