Bleiziffer, Sabine and Simonato, Matheus and Webb, John G. and Rodes-Cabau, Josep and Pibarot, Philippe and Kornowski, Ran and Windecker, Stephan and Erlebach, Magdalena and Duncan, Alison and Seiffert, Moritz and Unbehaun, Axel and Frerker, Christian and Conzelmann, Lars and Wijeysundera, Harindra and Kim, Won-Keun and Montorfano, Matteo and Latib, Azeem and Tchetche, Didier and Allali, Abdelhakim and Abdel-Wahab, Mohamed and Orvin, Katia and Stortecky, Stefan and Nissen, Henrik and Holzamer, Andreas and Urena, Marina and Testa, Luca and Agrifoglio, Marco and Whisenant, Brian and Sathananthan, Janarthanan and Napodano, Massimo and Landi, Antonio and Fiorina, Claudia and Zittermann, Armin and Veulemans, Verena and Sinning, Jan-Malte and Saia, Francesco and Brecker, Stephen and Presbitero, Patrizia and De Backer, Ole and Sondergaard, Lars and Bruschi, Giuseppe and Franco, Luis Nombela and Petronio, Anna Sonia and Barbanti, Marco and Cerillo, Alfredo and Spargias, Konstantinos and Schofer, Joachim and Cohen, Mauricio and Munoz-Garcia, Antonio and Finkelstein, Ariel and Adam, Matti and Serra, Vicenc and Teles, Rui Campante and Champagnac, Didier and Iadanza, Alessandro and Chodor, Piotr and Eggebrecht, Holger and Welsh, Robert and Caixeta, Adriano and Salizzoni, Stefano and Dager, Antonio and Auffret, Vincent and Cheema, Asim and Ubben, Timm and Ancona, Marco and Rudolph, Tanja and Gummert, Jan and Tseng, Elaine and Noble, Stephane and Bunc, Matjaz and Roberts, David and Kass, Malek and Gupta, Anuj and Leon, Martin B. and Dvir, Danny (2020) Long-term outcomes after transcatheter aortic valve implantation in failed bioprosthetic valves. EUROPEAN HEART JOURNAL, 41 (29). pp. 2731-2742. ISSN 0195-668X, 1522-9645
Full text not available from this repository. (Request a copy)Abstract
Aims Due to bioprosthetic valve degeneration, aortic valve-in-valve (ViV) procedures are increasingly performed. There are no data on long-term outcomes after aortic ViV. Our aim was to perform a large-scale assessment of long-term survival and reintervention after aortic ViV. Methods and results A total of 1006 aortic ViV procedures performed more than 5 years ago [mean age 77.7 +/- 9.7 years; 58.8% mate; median STS-PROM score 7.3% (4.2-12.0)] were included in the analysis. Patients were treated with Medtronic self-expandable valves (CoreVatve/Evolut, Medtronic Inc., Minneapolis, MN, USA) (n = 523, 52.0%), Edwards balloo-nexpandable valves (EBEV, SAPIEN/SAPIEN XT/SAPIEN 3, Edwards Lifesciences, Irvine, CA, USA) (n=435, 43.2%), and other devices (n =48, 4.8%). Survival was tower at 8 years in patients with small-failed bioprostheses [internal diameter (ID) < 20 mm] compared with those with large-failed bioprostheses (ID > 20 mm) (33.2% vs. 40.5%, P= 0.01). Independent correlates for mortality included smaller-failed bioprosthetic valves [hazard ratio (HR) 1.07 (95% confidence interval (CI) 1.02-1.13)], age [HR 1.21 (95% CI 1.01-1.45)], and non-transfemoral access [HR 1.43 (95% CI 1.11-1.84)]. There were 40 reinterventions after ViV. Independent correlates for all-cause reintervention included pre-existing severe prosthesis-patient mismatch [subhazard ratio (SHR) 4.34 (95% CI 1.31-14.39)], device malposition [SHR 3.75 (95% CI 1.36-10.35)], EBEV [SHR 3.34 (95% CI 1.26-8.85)], and age [SHR 0.59 (95% CI 0.44-0.78)]. Conclusions: The size of the original failed valve may influence long-term mortality, and the type of the transcatheter valve may influence the need for reintervention after aortic ViV. [GRAPHICS] .
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PROSTHESIS-PATIENT MISMATCH; EUROPEAN ASSOCIATION; AMERICAN SOCIETY; REPLACEMENT; RECOMMENDATIONS; TAVR; Aortic valve-in-valve; Reintervention; Severe prosthesis-patient mismatch; SAPIEN valve |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Herz-, Thorax- und herznahe Gefäßchirurgie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 17 Mar 2021 09:14 |
| Last Modified: | 17 Mar 2021 09:14 |
| URI: | https://pred.uni-regensburg.de/id/eprint/44066 |
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