Budde, Simon and Goerdeler, Felix and Floss, Johannes and Kreitmeier, Peter and Hicks, Elliot F. and Moscovitz, Oren and Seeberger, Peter H. and Davies, Huw M. L. and Reiser, Oliver (2020) Visible-light mediated oxidative ring expansion of anellated cyclopropanes to fused endoperoxides with antimalarial activity. ORGANIC CHEMISTRY FRONTIERS, 7 (14). pp. 1789-1795. ISSN 2052-4129,
Full text not available from this repository. (Request a copy)Abstract
A visible light mediated ring expansion of readily available carbo- and heterocyclic anellated cyclopropanes by molecular oxygen at ambient pressure has been developed. Tolerating a variety of functional groups, the reaction yields fused 1,2-dioxolanes, which were tested for antimalarial activity given their close analogy to the active principle of approved drugs such as artemisinin.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PHOTOINDUCED ELECTRON-TRANSFER; CYCLOADDITION REACTIONS; PHOTOOXYGENATION; 1,2-DIARYLCYCLOPROPANES; ANNULATION; FURANS; |
| Subjects: | 500 Science > 540 Chemistry & allied sciences |
| Divisions: | Chemistry and Pharmacy > Institut für Organische Chemie Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Oliver Reiser |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 18 Mar 2021 07:47 |
| Last Modified: | 18 Mar 2021 07:47 |
| URI: | https://pred.uni-regensburg.de/id/eprint/44188 |
Actions (login required)
 |
View Item |
