Notzon, S. and Deppermann, S. and Fallgatter, A. and Diemer, J. and Kroczek, A. and Domschke, K. and Zwanzger, P. and Ehlis, A. -C. (2015) Psychophysiological effects of an iTBS modulated virtual reality challenge including participants with spider phobia. BIOLOGICAL PSYCHOLOGY, 112. pp. 66-76. ISSN 0301-0511, 1873-6246
Full text not available from this repository. (Request a copy)Abstract
Preliminary evidence suggests beneficial effects of transcranial magnetic stimulation (TMS) on anxiety. The objective of this study was to investigate the effects of intermittent theta burst stimulation (iTBS) as a form of TMS on acute anxiety provoked by a virtual reality (VR) scenario. Participants with spider phobia (n = 41) and healthy controls (n = 42) were exposed to a spider scenario in VR after one session of iTBS over the prefrontal cortex or sham treatment. Participants with spider phobia reacted with more anxiety compared to healthy controls. Their heart rate and skin conductance increased compared to baseline. Contrary to expectations, iTBS did not influence these reactions, but modulated heart rate variability (HRV). Sympathetic influence on HRV showed an increase in the active iTBS group only. This study does not support the idea of beneficial effects of a single session of iTBS on anxiety, although other protocols or repeated sessions might be effective. (C) 2015 Elsevier B.V. All rights reserved.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | TRANSCRANIAL MAGNETIC STIMULATION; HEART-RATE-VARIABILITY; THETA-BURST STIMULATION; ANXIETY DISORDERS; MAJOR DEPRESSION; PREFRONTAL CORTEX; AVERSIVE AMPLIFICATION; PANIC DISORDER; QUESTIONNAIRE; EXPOSURE; Anxiety disorders; Heart rate (HR); Heart rate variability (HRV); iTBS; Skin conductance level (SCL); Specific phobia; Spider phobia; Theta burst stimulation; Transcranial magnetic stimulation (TMS); Virtual reality (VR) |
| Subjects: | 100 Philosophy & psychology > 150 Psychology |
| Divisions: | Psychology and Pedagogy > Institut für Psychologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 06 May 2019 07:47 |
| Last Modified: | 06 May 2019 07:47 |
| URI: | https://pred.uni-regensburg.de/id/eprint/4425 |
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