Thermal ablation of colorectal liver metastases: a position paper by an international panel of ablation experts, the interventional oncology sans frontiSres meeting 2013

Gillams, Alice and Goldberg, Nahum and Ahmed, Muneeb and Bale, Reto and Breen, David and Callstrom, Matthew and Chen, Min Hua and Choi, Byung Ihn and de Baere, Thierry and Dupuy, Damian and Gangi, Afshin and Gervais, Debra and Helmberger, Thomas and Jung, Ernst-Michael and Lee, Fred and Lencioni, Riccardo and Liang, Ping and Livraghi, Tito and Lu, David and Meloni, Franca and Pereira, Philippe and Piscaglia, Fabio and Rhim, Hyunchul and Salem, Riad and Sofocleous, Constantinos and Solomon, Stephen B. and Soulen, Michael and Tanaka, Masatoshi and Vogl, Thomas and Wood, Brad and Solbiati, Luigi (2015) Thermal ablation of colorectal liver metastases: a position paper by an international panel of ablation experts, the interventional oncology sans frontiSres meeting 2013. EUROPEAN RADIOLOGY, 25 (12). pp. 3438-3454. ISSN 0938-7994, 1432-1084

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Abstract

Previous attempts at meta-analysis and systematic review have not provided clear recommendations for the clinical application of thermal ablation in metastatic colorectal cancer. Many authors believe that the probability of gathering randomised controlled trial (RCT) data is low. Our aim is to provide a consensus document making recommendations on the appropriate application of thermal ablation in patients with colorectal liver metastases. This consensus paper was discussed by an expert panel at The Interventional Oncology Sans FrontiSres 2013. A literature review was presented. Tumour characteristics, ablation technique and different clinical applications were considered and the level of consensus was documented. Specific recommendations are made with regard to metastasis size, number, and location and ablation technique. Mean 31 % 5-year survival post-ablation in selected patients has resulted in acceptance of this therapy for those with technically inoperable but limited liver disease and those with limited liver reserve or co-morbidities that render them inoperable. In the absence of RCT data, it is our aim that this consensus document will facilitate judicious selection of the patients most likely to benefit from thermal ablation and provide a unified interventional oncological perspective for the use of this technology. aEuro cent Best results require due consideration of tumour size, number, volume and location. aEuro cent Ablation technology, imaging guidance and intra-procedural imaging assessment must be optimised. aEuro cent Accepted applications include inoperable disease due to tumour distribution or inadequate liver reserve. aEuro cent Other current indications include concurrent co-morbidity, patient choice and the test-of-time approach. aEuro cent Future applications may include resectable disease, e.g. for small solitary tumours.

Item Type: Article
Uncontrolled Keywords: ; Colorectal neoplasms; Liver neoplasms; Ablation techniques; Consensus; Clinical protocols
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Röntgendiagnostik
Depositing User: Dr. Gernot Deinzer
Date Deposited: 06 May 2019 07:52
Last Modified: 06 May 2019 07:52
URI: https://pred.uni-regensburg.de/id/eprint/4427

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