Monecke, Stefan and Koenig, Elisabeth and Earls, Megan R. and Leitner, Eva and Mueller, Elke and Wagner, Gabriel E. and Poitz, David M. and Jatzwauk, Lutz and Vremera, Teodora and Dorneanu, Olivia S. and Simbeck, Alexandra and Ambrosch, Andreas and Zollner-Schwetz, Ines and Krause, Robert and Ruppitsch, Werner and Schneider-Brachert, Wulf and Coleman, David C. and Steinmetz, Ivo and Ehricht, Ralf (2020) An epidemic CC1-MRSA-IV clone yields false-negative test results in molecular MRSA identification assays: a note of caution, Austria, Germany, Ireland, 2020. EUROSURVEILLANCE, 25 (25): 2000929. ISSN 1560-7917,
Full text not available from this repository. (Request a copy)Abstract
We investigated why a clinical meticillin-resistant Staphylococcus aureus (MRSA) isolate yielded false-negative results with some commercial PCR tests for MRSA detection. We found that an epidemic European CC1-MRSA-IV clone generally exhibits this behaviour. The failure of the assays was attributable to a large insertion in the orfx/SCCmec integration site. To ensure the reliability of molecular MRSA tests, it is vital to monitor emergence of new SCCmec types and junction sites.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ; |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 22 Mar 2021 06:00 |
| Last Modified: | 22 Mar 2021 06:00 |
| URI: | https://pred.uni-regensburg.de/id/eprint/44353 |
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