The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy

Ljungman, Per and Mikulska, Malgorzata and de la Camara, Rafael and Basak, Grzegorz W. and Chabannon, Christian and Corbacioglu, Selim and Duarte, Rafael and Dolstra, Harry and Lankester, Arjan C. and Mohty, Mohamad and Montoto, Silvia and Murray, John and de Latour, Regis Peffault and Snowden, John A. and Yakoub-Agha, Ibrahim and Verhouven, Bregje and Kroeger, Nicolaus and Styczynski, Jan (2020) The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy. BONE MARROW TRANSPLANTATION, 55 (11). pp. 2071-2076. ISSN 0268-3369, 1476-5365

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Abstract

The new coronavirus SARS-CoV-2 has rapidly spread over the world causing the disease by WHO called COVID-19. This pandemic poses unprecedented stress on the health care system including programs performing allogeneic and autologous hematopoietic cell transplantation (HCT) and cellular therapy such as with CAR T cells. Risk factors for severe disease include age and predisposing conditions such as cancer. The true impact on stem cell transplant and CAR T-cell recipients in unknown. The European Society for Blood and Marrow Transplantation (EBMT) has therefore developed recommendations for transplant programs and physicians caring for these patients. These guidelines were developed by experts from the Infectious Diseases Working Party and have been endorsed by EBMT's scientific council and board. This work intends to provide guidelines for transplant centers, management of transplant candidates and recipients, and donor issues until the COVID-19 pandemic has passed.

Item Type: Article
Uncontrolled Keywords: ;
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Abteilung für Pädiatrische Hämatologie, Onkologie und Stammzelltransplantation
Depositing User: Dr. Gernot Deinzer
Date Deposited: 24 Mar 2021 08:35
Last Modified: 24 Mar 2021 08:35
URI: https://pred.uni-regensburg.de/id/eprint/44573

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