Brunkhorst, F. M. and Weigand, M. A. and Pletz, M. and Gastmeier, P. and Lemmen, S. W. and Meier-Hellmann, A. and Ragaller, M. and Weyland, A. and Marx, G. and Bucher, M. and Gerlach, H. and Salzberger, B. and Grabein, B. and Welte, T. and Werdan, K. and Kluge, S. and Bone, H. G. and Putensen, C. and Rossaint, R. and Quintel, M. and Spies, C. and Weiss, B. and John, S. and Oppert, M. and Joerres, A. and Brenner, T. and Elke, G. and Gruendling, M. and Mayer, K. and Weimann, A. and Felbinger, T. W. and Axer, I. I. and Heller, H. and Gagelmann, N. (2020) S3 Guideline: Sepsis 2018. ANASTHESIOLOGIE & INTENSIVMEDIZIN, 61. pp. 178-188. ISSN 0170-5334, 1439-0256
Full text not available from this repository. (Request a copy)Abstract
Sepsis is an acute life-threatening organ dysfunction resulting from an inadequate host response to an infection. The diagnosis of sepsis-associated organ dysfunction should be based on a change of >= 2 points using the Sequential Organ Failure Assessment (SOFA) score. An intravenous crystalloid solution should be administered within the first 3 hours to achieve a haemodynamic stabilisation of the patient. A 0.9% NaCl solution should NOT be used. A schematic minimum infusion amount and a general target value for the mean arterial blood pressure are not recommended. Intravenous anti-infectives should be administered as soon as possible if possible within 1 hour after confirmed diagnosis. The application of an empirical broad-spectrum antibiotic or multiple antibiotics is recommended in order to account for all significant bacteria. Measurements of the procalcitonin value should be done to shorten the duration of antimicrobial therapy.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ; Sepsis; Diagnosis; Therapy; Management; Aftercare |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Lehrstuhl für Innere Medizin I |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 26 Mar 2021 07:43 |
| Last Modified: | 26 Mar 2021 07:43 |
| URI: | https://pred.uni-regensburg.de/id/eprint/44656 |
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