Outcome of pterygium excision after various surgical techniques-is excision with simple conjunctival closure still lege artis?

Eisenmann, K. and Zeman, F. and Helbig, H. and Gamulescu, M-A and Barth, T. (2020) Outcome of pterygium excision after various surgical techniques-is excision with simple conjunctival closure still lege artis? OPHTHALMOLOGE, 117 (4). pp. 359-365. ISSN 0941-293X, 1433-0423

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Abstract

Background There is no consensus about the best method for pterygium excision. Variable recurrence rates have been reported in the literature depending on the surgical technique. Objective To evaluate the postoperative outcome after pterygium excision depending on the preoperative extent of the pterygium and the surgical method. Material and methods A total of 109 patients (72 men, 37 women) who underwent 109 pterygium surgeries were retrospectively analyzed. In 87 cases postoperative data over a 5-year follow-up period were available. Besides recording the preoperative extent of the pterygium the functional outcome was analyzed and recurrence rates of the various techniques by simple excision with primary conjunctival closure (SE), conjunctival autograft (BHT) and amniotic membrane transplantation (AMT) were compared. Results Overall, recurrence was noted in 21 & x202f;%. The recurrence rate of SE was 20 & x202f;%. After BHT fewer recurrences (11 & x202f;%) were seen than after AMT (39 & x202f;%). After the intraoperative use of mitomycin C (MMC) more recurrences (31 & x202f;%) occurred than without the use of MMC (17%). In 45 & x202f;% of the cases delayed recurrence occurred after the first postoperative year. Conclusion In our opinion the method of SE is not obsolete. Good results can be achieved with SE in pterygia with a small extent. The lowest recurrence rate was seen after BHT; therefore, BHT is the method of choice in general and especially for larger pterygia. The higher recurrence rate after intraoperative use of MMC is probably caused by selection bias. Regular follow-up examinations are required beyond the first postoperative year for timely detection of delayed recurrence.

Item Type: Article
Uncontrolled Keywords: AMNIOTIC MEMBRANE TRANSPLANTATION; MITOMYCIN-C; AUTOGRAFT TRANSPLANTATION; RANDOMIZED-TRIAL; RECURRENCE; SURGERY; SIZE; Pterygium; Pterygium surgery; Conjunctival surgery; Conjunctival autograft; Amniotic membrane transplantation
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Lehrstuhl für Augenheilkunde
Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Klinische Studien
Depositing User: Dr. Gernot Deinzer
Date Deposited: 29 Mar 2021 05:01
Last Modified: 29 Mar 2021 05:01
URI: https://pred.uni-regensburg.de/id/eprint/44800

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