Self-reported infections in the German National Cohort (GNC) in the context of the current research landscape

Hassenstein, Max J. and Aarabi, Ghazal and Ahnert, Peter and Becher, Heiko and Franzke, Claus-Werner and Fricke, Julia and Krause, Gerard and Gloeckner, Stephan and Gottschick, Cornelia and Karch, Andre and Kemmling, Yvonne and Kerrinnes, Tobias and Lange, Berit and Mikolajczyk, Rafael and Nieters, Alexandra and Ott, Joerdis J. and Ahrens, Wolfgang and Berger, Klaus and Meinke-Franze, Claudia and Gastell, Sylvia and Guenther, Kathrin and Greiser, Karin Halina and Holleczek, Bernd and Horn, Johannes and Jaeschke, Lina and Jagodzinski, Annika and Jansen, Lina and Jochem, Carmen and Joeckel, Karl-Heinz and Kaaks, Rudolf and Krist, Lilian and Kuss, Oliver and Langer, Susan and Legath, Nicole and Leitzmann, Michael and Lieb, Wolfgang and Loeffler, Markus and Mangold, Nina and Michels, Karin B. and Meisinger, Christa and Obi, Nadia and Pischon, Tobias and Schikowski, Tamara and Schipf, Sabine and Schulze, Matthias B. and Stang, Andreas and Waniek, Sabina and Wirkner, Kerstin and Willich, Stefan N. and Castell, Stefanie (2020) Self-reported infections in the German National Cohort (GNC) in the context of the current research landscape. BUNDESGESUNDHEITSBLATT-GESUNDHEITSFORSCHUNG-GESUNDHEITSSCHUTZ, 63 (4). pp. 404-414. ISSN 1436-9990, 1437-1588

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Abstract

Background Infectious diseases continue to play an important role for disease perception, health-economic considerations and public health in Germany. In recent years, infectious diseases have been linked to the development of non-communicable diseases. Analyses of the German National Cohort (GNC) may provide deeper insights into this issue and pave the way for new targeted approaches in disease prevention. Objectives The aim was to describe the tools used to assess infectious diseases and to present initial data on infectious disease frequencies, as well as to relate the GNC assessment tools to data collection methods in other studies in Germany. Methods As part of the baseline examination, questions regarding infectious diseases were administered using both an interview and a self-administered touchscreen questionnaire. Data from the initial 101,787 GNC participants were analysed. Results In the interview, 0.2% (HIV/AIDS) to 8.6% (shingles) of respondents reported ever having a medical diagnosis of shingles, postherpetic neuralgia (in cases where shingles was reported), hepatitis B/C, HIV/AIDS, tuberculosis or sepsis if treated in hospital. In the questionnaire, 12% (cystitis) to 81% (upper respiratory tract infections) of respondents reported having experienced at least one occurrence of upper or lower respiratory tract infections, gastrointestinal infections, cystitis or fever within the past 12 months. Outlook The cross-sectional analyses of data and tools presented here - for example on determinants of susceptibility to self-reported infections - can be anticipated from the year 2021 onward. Beyond that, more extensive research into infectious disease epidemiology will follow, particularly once analyses of GNC biological materials have been performed.

Item Type: Article
Uncontrolled Keywords: URINARY-TRACT-INFECTION; HERPES-ZOSTER; DISEASE BURDEN; GLOBAL BURDEN; HEPATITIS-B; HEALTH; RISK; QUESTIONNAIRE; PREVALENCE; PNEUMONIA; Infectious diseases; Infectious disease epidemiology; German National Cohort (GNC); Cohort study; Communicable diseases; Epidemiology
Subjects: 600 Technology > 610 Medical sciences Medicine
Divisions: Medicine > Institut für Epidemiologie und Präventivmedizin > Lehrstuhl für Genetische Epidemiologie
Depositing User: Dr. Gernot Deinzer
Date Deposited: 29 Mar 2021 07:53
Last Modified: 29 Mar 2021 07:53
URI: https://pred.uni-regensburg.de/id/eprint/44919

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