Langer, Susan and Horn, Johannes and Kluttig, Alexander and Mikolajczyk, Rafael and Karrasch, Stefan and Schulz, Holger and Wichmann, Heinz-Erich and Linseisen, Jakob and Jaeschke, Lina and Pischon, Tobias and Fricke, Julia and Keil, Thomas and Ahrens, Wolfgang and Guenther, Kathrin and Kuss, Oliver and Schikowski, Tamara and Schmidt, Boerge and Joeckel, Karl-Heinz and Michels, Karin B. and Franzke, Claus-Werner and Becher, Heiko and Jagodzinski, Annika and Castell, Stefanie and Kemmling, Yvonne and Lieb, Wolfgang and Waniek, Sabina and Wirkner, Kerstin and Loeffler, Markus and Kaaks, Rudolf and Greiser, Karin Halina and Berger, Klaus and Legath, Nicole and Meinke-Franze, Claudia and Schipf, Sabine and Leitzmann, Michael and Baurecht, Hansjoerg and Weigl, Korbinian and Amitay, Efrat and Gottschick, Cornelia (2020) Occurrence of bronchial asthma and age at initial asthma diagnosis-first results of the German National Cohort. BUNDESGESUNDHEITSBLATT-GESUNDHEITSFORSCHUNG-GESUNDHEITSSCHUTZ, 63 (4). pp. 397-403. ISSN 1436-9990, 1437-1588
Full text not available from this repository. (Request a copy)Abstract
Background Asthma is one of the most common chronic diseases in both children and adults. Asthma first occurring in adulthood (adult-onset asthma, AOA) is associated with poorer prognosis compared to childhood-onset asthma (COA), which urgently calls for more research in this area. The aim of this work was to analyze the data on asthma collected in the German National Cohort and compare it with the German Health Interview and Examination Survey for Adults (DEGS), in particular regarding AOA. Material and Methods Our analysis was based on the dataset of the main questionnaire at mid-term of the German National Cohort baseline examination, comprising 101,723 participants. Variables considered in the analyses were self-reported diagnosis of asthma, age at first diagnosis, asthma treatment in the past 12 months, age, and sex. Results In the midterm dataset, 8.7% of women and 7.0% of men in the German National Cohort reported that they had ever been diagnosed with asthma. Approximately one third of participants with asthma received their initial diagnosis before their 18th birthday. COA affected 2.2% of women and 2.8% of men, whereas AOA affected 6.5% of women and 4.2% of men. During the previous 12 months, 33% of COA cases and 60% of AOA cases were medically treated. Conclusion The proportion of persons affected by asthma in the German National Cohort, as well as observed patterns regarding age and gender, corresponds to other data sources such as DEGS. However, in our analysis, the proportion of individuals with AOA was higher than described in the literature. The increase in cumulative asthma diagnoses with age is markedly steeper in younger participants, indicating a rising trend over time.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ADULT-ONSET ASTHMA; PREVALENCE; GENDER; RISK; Asthma; Chronic diseases; Respiratory diseases; General population; Cohort study |
| Subjects: | 600 Technology > 610 Medical sciences Medicine |
| Divisions: | Medicine > Institut für Epidemiologie und Präventivmedizin > Lehrstuhl für Genetische Epidemiologie |
| Depositing User: | Dr. Gernot Deinzer |
| Date Deposited: | 29 Mar 2021 09:29 |
| Last Modified: | 29 Mar 2021 09:29 |
| URI: | https://pred.uni-regensburg.de/id/eprint/44965 |
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